ISSN 1662-4009 (online)

ey0020.9-13 | Obesity and Insulin/Glucose Metabolism | ESPEYB20

9.13. Lack of evidence for a causal role of hyperinsulinemia in the progression of obesity in children and adolescents: a longitudinal study

R Halloun , A Galderisi , S Caprio , R Weiss

Brief summary: This longitudinal study aimed to determine if hyperinsulinemia and postprandial glucose levels could predict obesity progression in n=591 children and adolescents with obesity. The authors found no association between hyperinsulinemia, insulin secretion, low postprandial glucose levels, and an increase in obesity over a 2–4-year period.According to the carbohydrate-insulin model (1), diets with a high glycemic load (GL) promote weight...